Generating an allelic series of paintball mutants | Homework Helpers

Red pigment is produced in a fictional plant through the action of the gene paintball (P). Flowers of varying intensity from pale pink to bright red are made when the activity of the paintball enzyme is between 24 and 50. When the level of enzyme is below 24 the flowers fail to develop. When the level of enzyme activity exceeds 50, the flowers explode and spray red pigment on unsuspecting bystanders (hence the name of the gene). You decide to generate an allelic series of paintball mutants with the following activities.

Allele Activity
+ (wild type) 15 units
1 10 units
2 0 units
3 40 units
4 (dominant negative) -10 units

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P1 is ____________ to wild type.

                                                     P2 is ______________ to wild type.A) 

Should you wear a white shirt to work if you are looking at the progeny of a cross between two flowers with the genotype P1P3?

Allele 4 is a dominant negative mutation that interferes with normal protein function generating a phenotype when heterozygous with wild type. Is this mutation dominant to allele 3?A) B)  

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